The U.S. Department of Health and Human Services is deploying an AI platform by C3 AI to integrate NIH and Medicare/Medicaid data, enhancing biomedical research and public health analytics. This initiative supports HHS's AI strategy to improve healthcare program integrity and outcomes with secure, interoperable health data systems.

The Trump administration's 2026 draft budget proposes a one-third reduction in HHS funding, affecting NIH, CDC, CMS, and rural health programs, with key agency restructures and policy shifts.